Phosphorylation of HIC1 (Hypermethylated in Cancer 1) Ser694 by ATM is essential for DNA repair.
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rbFOX1/MBNL1 competition for CCUG RNA repeats binding contributes to myotonic dystrophy type 1/type 2 differences.
Nat Commun 2018; 9(1):2009
SynAggreg: A Multifunctional High-Throughput Technology for Precision Study of Amyloid Aggregation and Systematic Discovery of Synergistic Inhibitor Compounds.
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Mass Spectrometry of Mitochondrial Membrane Protein Complexes.
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Translation of Expanded CGG Repeats into FMRpolyG Is Pathogenic and May Contribute to Fragile X Tremor Ataxia Syndrome.
Neuron 2017; 93(2):331-347
KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification.
Nat Commun 2016; 7():13227
Cytoplasmic TAF2-TAF8-TAF10 complex provides evidence for nuclear holo-TFIID assembly from preformed submodules.
Nat Commun 2015; 6():6011
Subunits of ADA-two-A-containing (ATAC) or Spt-Ada-Gcn5-acetyltrasferase (SAGA) Coactivator Complexes Enhance the Acetyltransferase Activity of GCN5.
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Functional relationship between matrix metalloproteinase-11 and matrix metalloproteinase-14.
Cancer Med 2014; 3(5):1197-1210
Mof-associated complexes have overlapping and unique roles in regulating pluripotency in embryonic stem cells and during differentiation.
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Clusters of cerebellar Purkinje cells control their afferent climbing fiber discharge.
Proc Natl Acad Sci U S A 2013; 110(40):16223-8
Dissociation Kinetics of a Binary Complex in Solution by Protein Displacement.
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Mammalian frataxin controls sulfur production and iron entry during de novo Fe4S4 cluster assembly.
J Am Chem Soc 2013; 135(2):733-40
Sequestration of DROSHA and DGCR8 by Expanded CGG RNA Repeats Alters MicroRNA Processing in Fragile X-Associated Tremor/Ataxia Syndrome.
Cell Rep 2013; 3(3):869-80
An ABC Transporter with Two Periplasmic Binding Proteins Involved in Iron Acquisition in Pseudomonas aeruginosa.
ACS Chem Biol 2012; 7(12):2036-2045
In vivo topoisomerase I inhibition attenuates the expression of hypoxia-inducible factor 1alpha target genes and decreases tumor angiogenesis.
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KD4v: comprehensible knowledge discovery system for missense variant.
Nucleic Acids Res 2012; 40():W71–W75
Nxnl2 splicing results in dual functions in neuronal cell survival and maintenance of cell integrity.
Hum Mol Genet 2012; 21(10):2298-311
EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy
Nat Med 2011; 17(5):589-95
Epigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination
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Mammalian frataxin: an essential function for cellular viability through an interaction with a preformed ISCU/NFS1/ISD11 iron-sulfur assembly complex.
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