Publications

Phosphorylation of HIC1 (Hypermethylated in Cancer 1) Ser694 by ATM is essential for DNA repair.

Paget S, Dubuissez M, Page A, Dehennaut V, Loison I, Spruyt N, Leprince D

Biochem Biophys Res Commun 2021; 553():51-57

Reflux of Endoplasmic Reticulum proteins to the cytosol inactivates tumor suppressors.

Sicari D, Centonze FG, Pineau R, Le Reste PJ, Negroni L, Chat S, Mohtar MA, Thomas D, Gillet R, Hupp T, Chevet E, Igbaria A

EMBO Rep 2021; 22(5):e51412

rbFOX1/MBNL1 competition for CCUG RNA repeats binding contributes to myotonic dystrophy type 1/type 2 differences.

Sellier C(1), Cerro-Herreros E(2)(3), Blatter M(4), Freyermuth F(1), Gaucherot A(1), Ruffenach F(1), Sarkar P(5), Puymirat J(6), Udd B(7)(8)(9), Day JW(10), Meola G(11)(12), Bassez G(13), Fujimura H(14), Takahashi MP(15), Schoser B(16), Furling D(13), Artero R(2)(3), Allain FHT(4), Llamusi B(17)(18), Charlet-Berguerand N(19)(20)(21)(22).

Nat Commun 2018; 9(1):2009

SynAggreg: A Multifunctional High-Throughput Technology for Precision Study of Amyloid Aggregation and Systematic Discovery of Synergistic Inhibitor Compounds.

Aviolat H(1), Nomine Y(1), Gioria S(2), Bonhoure A(1), Hoffmann D(1), Ruhlmann C(1), Nierengarten H(3), Ruffenach F(1), Villa P(4), Trottier Y(5), Klein FAC(6).

J Mol Biol 2018; 430(24):5257-5279

The O-beta-linked N-acetylglucosaminylation of the Lamin B receptor and its impact on DNA binding and phosphorylation.

Smet-Nocca C(1), Page A(2), Cantrelle FX(3), Nikolakaki E(4), Landrieu I(3), Giannakouros T(4).

Biochim Biophys Acta 2018; 1862(4):825-835

Integrated and Quantitative Proteomics of Human Tumors.

Yakkioui Y(1), Temel Y(1), Chevet E(2), Negroni L(3).

Methods Enzymol 2017; 586():229-246

Mass Spectrometry of Mitochondrial Membrane Protein Complexes.

Negroni L(1)(2), Zivy M(3), Lemaire C(4).

Methods Mol Biol 2017; 1635():233-246

Translation of Expanded CGG Repeats into FMRpolyG Is Pathogenic and May Contribute to Fragile X Tremor Ataxia Syndrome.

Sellier C, Buijsen RAM, He F, Natla S, Jung L, Tropel P, Gaucherot A, Jacobs H, Meziane H, Vincent A, Champy MF, Sorg T, Pavlovic G, Wattenhofer-Donze M, Birling MC, Oulad-Abdelghani M, Eberling P, Ruffenach F, Joint M, Anheim M, Martinez-Cerdeno V, Tassone F, Willemsen R, Hukema RK, Viville S, Martinat C, Todd PK, Charlet-Berguerand N

Neuron 2017; 93(2):331-347

Translation of Expanded CGG Repeats into FMRpolyG Is Pathogenic and May Contribute to Fragile X Tremor Ataxia Syndrome.

Sellier C, Buijsen RAM, He F, Natla S, Jung L, Tropel P, Gaucherot A, Jacobs H, Meziane H, Vincent A, Champy MF, Sorg T, Pavlovic G, Wattenhofer-Donze M, Birling MC, Oulad-Abdelghani M, Eberling P, Ruffenach F, Joint M, Anheim M, Martinez-Cerdeno V, Tassone F, Willemsen R, Hukema RK, Viville S, Martinat C, Todd PK, Charlet-Berguerand N

Neuron 2017; 93(2):331-347

Integrated and Quantitative Proteomics of Human Tumors

Y. Yakkioui, Y. Temel, E. Chevet‡, L. Negroni

Methods in Enzymology 2016; 586():229-246

KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification.

Fournier M(1,)(2,)(3,)(4,)(5), Orpinell M(6), Grauffel C(1,)(2,)(3,)(4), Scheer E(1,)(2,)(3,)(4), Garnier JM(1,)(2,)(3,)(4), Ye T(1,)(2,)(3,)(4), Chavant V(1,)(2,)(3,)(4), Joint M(1,)(2,)(3,)(4), Esashi F(5), Dejaegere A(1,)(2,)(3,)(4), Gonczy P(6), Tora L(1,)(2,)(3,)(4).

Nat Commun 2016; 7():13227

Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death.

Sellier C(1), Campanari ML(2), Julie Corbier C(3), Gaucherot A(3), Kolb-Cheynel I(3), Oulad-Abdelghani M(3), Ruffenach F(3), Page A(3), Ciura S(2), Kabashi E(2), Charlet-Berguerand N(1).

EMBO J 2016; 35(12):1276-1297

Cytoplasmic TAF2-TAF8-TAF10 complex provides evidence for nuclear holo-TFIID assembly from preformed submodules.

Trowitzsch S(1), Viola C(1), Scheer E(2), Conic S(2), Chavant V(3), Fournier M(2), Papai G(4), Ebong IO(5), Schaffitzel C(1), Zou J(6), Haffke M(1), Rappsilber J(7), Robinson CV(5), Schultz P(4), Tora L(2), Berger I(8).

Nat Commun 2015; 6():6011

Subunits of ADA-two-A-containing (ATAC) or Spt-Ada-Gcn5-acetyltrasferase (SAGA) Coactivator Complexes Enhance the Acetyltransferase Activity of GCN5.

Riss A(1), Scheer E(1), Joint M(2), Trowitzsch S(3), Berger I(3), Tora L(4).

J Biol Chem 2015; 290(48):28997-9009

The Gibbs-plaid biclustering model

Thierry Chekouo, Alejandro Murua, and Wolfgang Raffelsberger

The Annals of Applied Statistics 2015; 9(3):1643-1670

The Gibbs-plaid biclustering model

Thierry Chekouo Alejandro Murua Wolfgang Raffelsberger

The Annals of Applied Statistics 2015; 9(3):1643-1670

Thioredoxin rod-derived cone viability factor protects against photooxidative retinal damage.

Elachouri G(1), Lee-Rivera I(1), Clérin E(1), Argentini M(1), Fridlich R(1), Blond F(1), Ferracane V(1), Yang Y(1), Raffelsberger W(2), Wan J(3), Bennett J(4), Sahel JA(1), Zack DJ(5), Léveillard T(6).

Free Radic Biol Med 2015; 81():22-9

Functional relationship between matrix metalloproteinase-11 and matrix metalloproteinase-14.

Buache E(1), Thai R, Wendling C, Alpy F, Page A, Chenard MP, Dive V, Ruff M, Dejaegere A, Tomasetto C, Rio MC.

Cancer Med 2014; 3(5):1197-1210

Mapping the Deubiquitination Module within the SAGA Complex.

Durand A(1), Bonnet J(2), Fournier M(2), Chavant V(3), Schultz P(4).

Structure 2014; 22(11):1553-1559

Mof-associated complexes have overlapping and unique roles in regulating pluripotency in embryonic stem cells and during differentiation.

Ravens S(1), Fournier M(1), Ye T(2), Stierle M(1), Dembele D(2), Chavant V(3), Tora L(1).

Elife 2014; 3():e02104

The molecular signature of the stroma response in prostate cancer-induced osteoblastic bone metastasis highlights expansion of hematopoietic and prostate epithelial stem cell niches.

Özdemir BC(1), Hensel J(1), Secondini C(1), Wetterwald A(1), Schwaninger R(1), Fleischmann A(2), Raffelsberger W(3), Poch O(4), Delorenzi M(5), Temanni R(6), Mills IG(7), van der Pluijm G(8), Thalmann GN(1), Cecchini MG(1).

PLoS One 2014; 9(12):e114530

Clusters of cerebellar Purkinje cells control their afferent climbing fiber discharge.

Chaumont J(1), Guyon N, Valera AM, Dugué GP, Popa D, Marcaggi P, Gautheron V, Reibel-Foisset S, Dieudonné S, Stephan A, Barrot M, Cassel JC, Dupont JL, Doussau F, Poulain B, Selimi F, Léna C, Isope P.

Proc Natl Acad Sci U S A 2013; 110(40):16223-8

Dissociation Kinetics of a Binary Complex in Solution by Protein Displacement.

Launay H, Parent B, Page A, Hanoulle X, Lippens G.

Angew Chem Int Ed Engl 2013; 52(48):12587-91

Mammalian frataxin controls sulfur production and iron entry during de novo Fe4S4 cluster assembly.

Colin F, Martelli A, Clémancey M, Latour JM, Gambarelli S, Zeppieri L, Birck C, Page A, Puccio H, Ollagnier de Choudens S.

J Am Chem Soc 2013; 135(2):733-40

Sequestration of DROSHA and DGCR8 by Expanded CGG RNA Repeats Alters MicroRNA Processing in Fragile X-Associated Tremor/Ataxia Syndrome.

Sellier C, Freyermuth F, Tabet R, Tran T, He F, Ruffenach F, Alunni V, Moine H, Thibault C, Page A, Tassone F, Willemsen R, Disney MD, Hagerman PJ, Todd PK, Charlet-Berguerand N.

Cell Rep 2013; 3(3):869-80

The cohesin complex regulates immunoglobulin class switch recombination.

Thomas-Claudepierre AS, Schiavo E, Heyer V, Fournier M, Page A, Robert I, Reina-San-Martin B.

J Exp Med 2013; 210(12):2495-502

An ABC Transporter with Two Periplasmic Binding Proteins Involved in Iron Acquisition in Pseudomonas aeruginosa.

Brillet K, Ruffenach F, Adams H, Journet L, Gasser V, Hoegy F, Guillon L, Hannauer M, Page A, Schalk IJ.

ACS Chem Biol 2012; 7(12):2036-2045

In vivo topoisomerase I inhibition attenuates the expression of hypoxia-inducible factor 1alpha target genes and decreases tumor angiogenesis.

Guérin E(1), Raffelsberger W, Pencreach E, Maier A, Neuville A, Schneider A, Bachellier P, Rohr S, Petitprez A, Poch O, Moras D, Oudet P, Larsen AK, Gaub MP, Guenot D.

Mol Med 2012; 18():83-94

KD4v: comprehensible knowledge discovery system for missense variant.

Luu TD, Rusu A, Walter V, Linard B, Poidevin L, Ripp R, Moulinier L, Muller J, Raffelsberger W, Wicker N, Lecompte O, Thompson JD, Poch O, Nguyen H.

Nucleic Acids Res 2012; 40():W71–W75

Nxnl2 splicing results in dual functions in neuronal cell survival and maintenance of cell integrity.

Jaillard C(1), Mouret A, Niepon ML, Clérin E, Yang Y, Lee-Rivera I, Aït-Ali N, Millet-Puel G, Cronin T, Sedmak T, Raffelsberger W, Kinzel B, Trembleau A, Poch O, Bennett J, Wolfrum U, Lledo PM, Sahel JA, Léveillard T.

Hum Mol Genet 2012; 21(10):2298-311

Pro-nerve growth factor induces autocrine stimulation of breast cancer cell invasion through TRKA and sortilin.

Demont Y, Corbet C, Page A, Ataman-Onal Y, Choquet-Kastylevsky G, Fliniaux I, Le Bourhis X, Toillon RA, Bradshaw RA, Hondermarck H.

J Biol Chem 2012; 287(3):1923-31

EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy

Lupberger J., Zeisel M.B., Xiao F., Thumann C., Fofana I., Zona L., Davis C., Mee C.J., Turek M., Gorke S., Royer C., Fischer B., Zahid M.N., Lavillette D., Fresquet J., Cosset F.L., Rothenberg S.M., Pietschmann T., Patel A.H., Pessaux P., Doffoel M., Raffelsberger W., Poch O., McKeating J.A., Brino L., Baumert T.F.

Nat Med 2011; 17(5):589-95

Epigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination

Jeevan-Raj B.P., Robert I., Heyer V., Page A., Wang J.H., Cammas F., Alt F.W., Losson R., Reina-San-Martin B.

J Exp Med 2011; 208(8):1649-60

Mammalian frataxin: an essential function for cellular viability through an interaction with a preformed ISCU/NFS1/ISD11 iron-sulfur assembly complex.

Schmucker S, Martelli A, Colin F, Page A, Wattenhofer-Donzé M, Reutenauer L, Puccio H.

PLoS One 2011; 6(1):e16199

Transcriptomic analysis of human retinal detachment reveals both inflammatory response and photoreceptor death.

Delyfer MN(1), Raffelsberger W, Mercier D, Korobelnik JF, Gaudric A, Charteris DG, Tadayoni R, Metge F, Caputo G, Barale PO, Ripp R, Muller JD, Poch O, Sahel JA, Léveillard T.

PLoS One 2011; 6(12):e28791

Identification of the N-glycosylation sites on recombinant bovine CD38 expressed in Pichia pastoris: their impact on enzyme stability and catalytic activity

Muller-Steffner H., Kuhn I., Argentini M., Schuber F.

Protein Expr Purif 2010; 70(2):151-7

An Optimized MALDI Mass Spectrometry Method for Improved Detection of Lysine/Arginine/Histidine Free Peptides

Argentini M., Strub J.M., Carapito C., Sanglier S., Van-Dorsselaer A.

J Proteome Res 2008; 7(11):5062-5069